分析化学，理学博士，讲师，硕士生导师

电话：15111429554；电子邮箱：leiyanli222@126.com

【个人简介】 

雷艳丽，女，1990年出生，湖南郴州人。本科毕业于江南大学，硕博毕业于湖南大学，2019年入职长沙理工大学，现为讲师，硕士研究生导师，湖南省细胞化学重点实验室核心成员。主要从事核酸适配体探针的设计及生物医学、食品安全的应用研究。已主持湖南省自然科学基金青年项目、湖南省教育厅一般项目、化学生物传感与计量学国家重点实验室开发基金等多项研究课题，在Angew. Chem.、Theranostics、Anal. Chem.、Chem. Commun.等SCI源期刊发表论文20余篇，申请发明专利2项。

【主讲课程】：

研究生：《生命分析化学》、《药物分析与检测》

本科生：《生物工艺学》、《药物分析》 

【主要研究领域】：

1.功能核酸探针的设计与分析应用

2.细胞和小动物活体成像研究

3.化学传感器在食品安全分析中的应用

【5篇代表性论文】:

1.Yanli Lei, Jinlu Tang, Xiaoxiao He, Hui Shi,* Yu Zeng, Haiyan Sun, and Kemin Wang*. In Situ Modulating DNAzyme Activity and Internalization Behavior with Acid-Initiated Reconfigurable DNA Nanodevice for Activatable Theranostic. Anal. Chem., 2021, 93, 5629-5634. (IF:6.986)

2.Lihua Zhang, Zhen Zou, Yanli Lei,* Zhihe Qing, Yu Zeng, Haiyan Sun, Feng Feng* and Ronghua Yang*. Bidirectional modulation of microRNA with a clamp-like triplex switch for enhanced and programmed gene therapy. Chem. Commun., 2021, 57, 12131-12134. (IF: 6.222)

3.Lifang Chen,# Shuohui Xing,# Yanli Lei,# Qiaoshu Chen, Zhen Zou, Ke Quan, Zhihe Qing*, Juewen Liu, and Ronghua Yang*. A Glucose-Powered Activatable Nanozyme Breaking pH and H2O2 Limitations for Treating Diabetic Infections. Angew. Chem. Int. Ed. 2021, 60, 23534–23539. (IF: 15.336)

4.Jun Li, Ke Yi, Yanli Lei,* Zhihe Qing, Zhen Zou, Yuedong Zhang, Haiyan Sun, Ronghua Yang*. Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer. Chem. Commun., 2020, 56, 6285. (IF: 6.222)

5.Yanli Lei, Zhenzhen Qiao, Jinlu Tang, Xiaoxiao He, Hui Shi,* Xiaosheng Ye, Lv’an Yan, Dinggeng He and Kemin Wang*. DNA nanotriangle-scaffolded multivalent activatable aptamer probe with ultralow background and robust stability for cancer theranostics. Theranostics, 2018, 8, 4062-4071. (IF: 11.556)